Duke has always been treated well in Madison Square Garden, the site of this year’s East Regional; Villanova has had some really nice moments in that building, too. A key player in this game will be Amile Jefferson, who is a fabulous defender, and his interior footwork and quickness are excellent. Expect Duke to attack Kris Jenkins at every opportunity and make him guard. Duke wins in a great game, and a close one, to advance to the Final Four. Duke has the most talented roster in the game, and is finally healthy: